STS-1 (OFT-1)
STS-2 (OFT-2)
1982
STS-3 (OFT-3)
STS-4 (OFT-4)
STS-5 (First Operational Mission; first 4-astronaut crew)
1983
STS-6(TDRS-A, First flight of Challenger, First Shuttle Spacewalk)
STS-7 (First U.S. Woman in Space, First Rendez-Vous & RMS Grapple, first 5-astronaut crew)
STS-8 (First black astronaut; first night launch & landing)
STS-9 (First Spacelab-Mission, first non-U.S. citizen, first 6-astronaut crew)
1984
41B (First use of Manned Maneuvering Unit; Palapa/Westar loss)
41C (First Shuttle Satellite Rescue mission (Solar Max); LDEF Deploy)
41D (First flight of Discovery, First pad abort; Solar Panel-test; first commercial "passenger")
41G (First 7-astronaut crew; first spacewalk by U.S. woman)
51A (Palapa/Westar rescue mission)
1985
51C (First DoD Mission)
51D (Senator Jake Garn; Syncom engine failure)
51B (Spacelab-3)
51G (Star Wars test; two foreign astronauts)
51F (Spacelab-2, first Abort to Orbit)
51I (Syncom Rescue Mission)
51J (First flight of Atlantis; DoD Mission)
61A (Spacelab D1, first 8-astronaut crew, three foreign astronauts)
61B (Space Station constuction tests)
1986
61C (Representative Bill Nelson)
51L (Challenger Accident)
1988
STS-26 (Return to Flight; TDRS-C)
STS-27 (DoD Mission)
1989
STS-29 (TDRS-D)
STS-30 (Magellan)
STS-28 (DoD Mission)
STS-34 (Galileo)
STS-33 (DoD Mission)
1990
STS-32 (LDEF-retrieval)
STS-36 (DoD Mission)
STS-31 (Hubble Space Telescope deploy)
STS-41 (Ulysses)
STS-38 (DoD Mission)
STS-35 (Astro-1)
1991
STS-37 (Gamma Ray Observatory)
STS-39 (Star Wars tests)
STS-40 (Spacelab Life Sciences-1)
STS-43 (TDRS-E)
STS-48 (Upper Atmosphere Research Sattellite)
STS-44 (DoD Mission; DSP)
1992
STS-42 (International Microgravity Lab-1)
STS-45 (Atlas-1)
STS-49 (First flight of Endeavour; Intelsat reboost)
- STS-50 (U.S. Microgravity Lab-1)
STS-46 (Tethered Satellite System-1; Eureca deploy)
- STS-47 (Spacelab-J)
- STS-52 (U.S. Microgravity Payload-1, Lageos)
-
STS-53 (DoD Mission)
1993
STS-54 (TDRS-F)
- STS-56 (Atlas-2)
STS-55 (Spacelab-D2
- STS-57 (First flight of Spacehab; Eureca-retrieval)
STS-51 (Advanced Communications Technology Satellite)
STS-58 (Spacelab Life Sciences-2)
STS-61 (Hubble Servicing Mission 1)
1994
STS-60 (Wake Shield Facility; first Russian on U.S. Shuttle)
- STS-62 (USMP-2)
STS-59 (Shuttle Radar Lab-1)
STS-65 (IML-2)
STS-64 (Lidar in Space Technology Exp. (LITE); first flight of SAFER)
STS-68 (SRL-2)
STS-66 (Atlas-3)
1995
STS-63 (First Shuttle/Mir rendezvous)
STS-67 (Astro-2)
STS-71 (First Shuttle-Mir docking)
STS-70 (TDRS-G; Woodpeckers drill holes in External Tank)
STS-69 (Wake Shield Facility-2)
STS-73 (USML-2)
STS-74 (Shuttle-Mir Mission 2; Docking Module)
1996
STS-72 (Space Flyer Unit retrieval)
STS-75 (USMP-3; Tethered Satellite System-2)
STS-76 (Shuttle-Mir Mission 3, Lucid stays at Mir)
STS-77 (Inflatable Antenna Experiment)
STS-78 (Life and Microgravity Sciences-1)
STS-79 (Shuttle-Mir Mission 4; Lucid replaced by Blaha)
STS-80 (Wake Shield Facility-3; Spacewalk cancelled due to stuck hatch)
1997
STS-81 (Shuttle-Mir Mission 5; Blaha replaced by Linenger)
STS-82 (Hubble Space Telescope Servicing Mission 2)
STS-83 (Microgravity Science Lab-1, Mission aborted)
STS-84 (Shuttle-Mir Mission 6; Linenger replaced by Foale)
STS-94 (Microgravity Science Lab-1 Reflight)
STS-85 (SPAS)
STS-86 (Shuttle-Mir Mission 7; Foale replaced by Wolf)
STS-87 (SPARTAN Rescue)
1998
STS-89 (Shuttle-Mir Mission 8; Wolf replaced by Thomas)
STS-90 (Final Spacelab mission)
STS-91 (Final Shuttle-Mir Mission)
STS-95 (John Glenn)
STS-88 (Space Station Construction Mission 1: Unity / Zarya)
1999
STS-96 (Space Station Mission 2: Supply, Russian Crane)
STS-93 (Advanced X-ray Astronomical Facility; First Woman Commander)
STS-103 (Hubble Space Telescope Servicing Mission-3)
2000
STS-99 (Shuttle Topography Radar Mapping)
STS-101 (Space Station Mission 3: Supply)
STS-106 (Space Station Mission 4: Supply)
STS-92 (Space Station Mission 5: Z1 and PMA-3; 100th Shuttle Mission)
STS-97 (Space Station Mission 6, P6 Truss)
2001
STS-98 (Space Station Mission 7, U.S. Destiny Laboratory)
STS-102 (Space Station Mission 8, first crew-change)
STS-100 (Space Station Mission 9)
STS-104 (Space Station Mission 10, Airlock)
STS-105 (Space Station Mission 11, second crew-change)
STS-108 (Space Station Mission 12, third crew-change)
2002
STS-109 (Hubble Space Telescope Servicing Mission-4)
STS-110 (ISS Mission 13, S0-truss)
STS-111 (ISS Mission 14, MPLM, UF-2, MBS)
STS-112 (ISS Mission 15, S1 truss)
STS-113 (Gus Loria, Donald Thomas)
STS-113 (ISS Mission 16, P1 truss, crew change)
2003
STS-107 (Columbia accident, First Israeli astronaut)
2004
STS-114 (Moschenko)
STS-114 (Exp-6 & 7)
STS-114 (Return to Flight, ISS Mission 17)
STS-121 (ISS Mission 18, crew change)
2005
STS-115 (ISS Mission 19, P3, P4 truss, Solar Arrays)
STS-116 (ISS Mission 20, crew rotation)
STS-117 (ISS Mission 21)
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